Low-dose nitrous oxide and dyspnoea

P110: Nitrous Oxide and Neuroinflammation

Nitrous oxide was an anaesthetic gas that was used for many years. There were many anaesthetic drugs in operations  with many side effects. Nitrous oxide had some side effects too. But it was a safe gas in many times. In hospital personnel who worked in operating rooms exposure to this gas was important. The objective of this study was the introduction of nitrous oxide and neurologic side ...

A low concentration of nitrous oxide reduces dyspnoea produced by a combination of hypercapnia and severe elastic load.

We have measured how a low concentration of nitrous oxide affected respiratory sensation and ventilation. Severe dyspnoea was induced in nine normal subjects by a combination of hypercapnia and inspiratory elastic load (50 cm H2O litre-1). Subjects were asked to rate their sensation of respiratory discomfort using a visual analogue scale (VAS) while breathing either 20% nitrous oxide or 20% nit...

Aerobic denitrifying bacteria that produce low levels of nitrous oxide.

Most denitrifiers produce nitrous oxide (N(2)O) instead of dinitrogen (N(2)) under aerobic conditions. We isolated and characterized novel aerobic denitrifiers that produce low levels of N(2)O under aerobic conditions. We monitored the denitrification activities of two of the isolates, strains TR2 and K50, in batch and continuous cultures. Both strains reduced nitrate (NO(3)(-)) to N(2) at rate...

Low Levels of Nitrous Oxide Aerobic Denitrifying Bacteria That Produce

Nitrous Oxide for the Treatment of Chronic Low Back Pain.

BACKGROUND Neuropathic back pain is mediated, at least partially, by N-methyl-D-aspartate (NMDA) receptors. Nitrous oxide (N2O) is an NMDA receptor antagonist. We therefore tested the primary hypothesis that patients receiving N2O have lower pain scores after epidural steroid injection than patients not receiving N2O. METHODS Patients with recurrent low back pain scheduled for epidural steroi...